{"id":15781,"date":"2020-12-06T05:20:26","date_gmt":"2020-12-06T05:20:26","guid":{"rendered":"https:\/\/yourchennai.com\/?p=15781"},"modified":"2020-12-06T05:22:08","modified_gmt":"2020-12-06T05:22:08","slug":"suburban-diagnostics-conducts-a-research-on-the-pattern-of-antibodies-and-antigens-present-in-covid-19-patients","status":"publish","type":"post","link":"https:\/\/yourchennai.com\/index.php\/2020\/12\/06\/suburban-diagnostics-conducts-a-research-on-the-pattern-of-antibodies-and-antigens-present-in-covid-19-patients\/","title":{"rendered":"Suburban diagnostics conducts a research on the pattern of antibodies and antigens present in COVID-19 patients"},"content":{"rendered":"
<\/div>

Observes a falling trend in the COVID-19 positive cases in Mumbai from June to November 2020<\/strong><\/em><\/h3>\n

Suburban Diagnostics, in their attempt to objectify their diagnostic and management strategies, conducted a research on 83 patients with a known history of COVID-19. These patients were followed up on with serial antibody tests to study the sero-conversion and the trend of antibody response post infection. Out of the 83 patients, 64% (53 patients) had symptomatic COVID-19 infection and 36% (30 patients) had completely asymptomatic infection.<\/p>\n

When followed up for 120-150 days post infection, 92% were positive for antibodies and 8% were still negative. <\/b>Of the patients who completed 180 days post diagnosis, 90% were antibody positive. This figure is liable to change once all the patients being followed up complete 180 days and are tested.<\/p>\n

When following up with antibody testing amongst the 83 patients, 88% showed a rise in titres at 60-90 days, while 4% cases showed a dip and 8% cases were still non-reactive. At 90-120 days, 55% cases showed rising antibody values, 35% showed a dip in these values while 2% cases showed a plateau in antibody values and 8% were still non-reactive. At 120-150 days, 37% cases showed rising antibody values, 55% showed a dip in these values and 8% were still non-reactive.<\/p>\n

The table below shows that, from June to November, 2020 there was a significant rise in the percentage of patients who developed antibodies. Out of the total 37,646 tests conducted it was found that around 14,080 which is around 37.4% of the patients had developed COVID-19 antibodies.<\/p>\n\n\n\n\n\n\n\n\n\n\n
\n

Month<\/b><\/p>\n<\/td>\n

Number of antibody tests done<\/b><\/td>\nCOVID Antibody Positivity Rate<\/b><\/td>\n<\/tr>\n
\n

June<\/p>\n<\/td>\n

\n

190<\/p>\n<\/td>\n

\n

27.9%<\/p>\n<\/td>\n<\/tr>\n

\n

July<\/p>\n<\/td>\n

\n

6204<\/p>\n<\/td>\n

\n

21.8%<\/p>\n<\/td>\n<\/tr>\n

\n

August<\/p>\n<\/td>\n

\n

6234<\/p>\n<\/td>\n

\n

30.6%<\/p>\n<\/td>\n<\/tr>\n

\n

September<\/p>\n<\/td>\n

\n

10535<\/p>\n<\/td>\n

\n

36.7%<\/p>\n<\/td>\n<\/tr>\n

\n

October<\/p>\n<\/td>\n

\n

9238<\/p>\n<\/td>\n

\n

48.0%<\/p>\n<\/td>\n<\/tr>\n

\n

November<\/p>\n<\/td>\n

\n

5245<\/p>\n<\/td>\n

\n

46.8%<\/p>\n<\/td>\n<\/tr>\n

Grand Total<\/b><\/td>\n\n

37,646<\/b><\/p>\n<\/td>\n

\n

37.4%<\/b><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

One more study conducted on a total of 200 patients by Suburban Diagnostics was to understand the concordance between the rapid antigen test and the RT-PCR test with different cycle threshold (CT) values. In this study, the patients were evaluated for the COVID-19 infection by the rapid antigen method and the RT-PCR method, both. The conclusion of the study is that the rapid antigen test was 100% specific with no false positives found and had a 60% sensitivity compared to the RT-PCR test. It showed a lower sensitivity of 32% in asymptomatic patients. The CT value correlation showed that 63% cases that the antigen test proved negative but the RT-PCR test proved positive had borderline CT values corresponding to low viral titres. A RT-PCR analysis was also processed on more than 3.7 lac samples declared 70.7% results were negative and 29.3% were positive.<\/p>\n

The table below represents the number of RT-PCR tests carried out in each month between May and November, 2020. A significant fall can be seen\u00a0in the percentage of patients who tested positive. Out of the total 4,06,780 tests conducted it was found that around 1,04,949 which is around 25.8% of the patients were COVID-19 positive.<\/p>\n\n\n\n\n\n\n\n\n\n\n\n
\n

Month<\/b><\/p>\n<\/td>\n

\n

Number of diagnostic tests done<\/b><\/p>\n<\/td>\n

\n

SARS-CoV-2 virus positivity rate<\/b><\/p>\n<\/td>\n<\/tr>\n

\n

May<\/p>\n<\/td>\n

\n

18044<\/p>\n<\/td>\n

\n

29.3%<\/p>\n<\/td>\n<\/tr>\n

\n

June<\/p>\n<\/td>\n

\n

30161<\/p>\n<\/td>\n

\n

35.0%<\/p>\n<\/td>\n<\/tr>\n

\n

July<\/p>\n<\/td>\n

\n

55543<\/p>\n<\/td>\n

\n

35.1%<\/p>\n<\/td>\n<\/tr>\n

\n

August<\/p>\n<\/td>\n

\n

59943<\/p>\n<\/td>\n

\n

27.8%<\/p>\n<\/td>\n<\/tr>\n

\n

September<\/p>\n<\/td>\n

\n

96201<\/p>\n<\/td>\n

\n

30.6%<\/p>\n<\/td>\n<\/tr>\n

\n

October<\/p>\n<\/td>\n

\n

81802<\/p>\n<\/td>\n

\n

19.6%<\/p>\n<\/td>\n<\/tr>\n

\n

November<\/p>\n<\/td>\n

\n

65086<\/p>\n<\/td>\n

\n

11.3%<\/p>\n<\/td>\n<\/tr>\n

Grand Total<\/b><\/td>\n\n

4,06,780<\/b><\/p>\n<\/td>\n

\n

25.8%<\/b><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

In relation to antibody development, a rising trend has been seen since July in the city of Mumbai and a falling trend of COVID-19 virus positivity rate has been seen from July till November after a peak in July, 2020.<\/p>\n","protected":false},"excerpt":{"rendered":"

Observes a falling trend in the COVID-19 positive cases in Mumbai from June to November 2020 Suburban Diagnostics, in their attempt to objectify their<\/p>\n","protected":false},"author":1,"featured_media":15782,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[10,7],"tags":[19089,20461,15212,739,20462,20460],"class_list":["post-15781","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health-hospital-daycare","category-lifestyle-health-hotel-leisure-food-fashion","tag-antibodies","tag-antigens","tag-covid-19","tag-mumbai","tag-rt-pcr-test","tag-suburban-diagnostics"],"views":636,"jetpack_featured_media_url":"https:\/\/yourchennai.com\/wp-content\/uploads\/2020\/12\/Suburban-Diagnostics-Logo.jpg","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/yourchennai.com\/index.php\/wp-json\/wp\/v2\/posts\/15781","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/yourchennai.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/yourchennai.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/yourchennai.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/yourchennai.com\/index.php\/wp-json\/wp\/v2\/comments?post=15781"}],"version-history":[{"count":2,"href":"https:\/\/yourchennai.com\/index.php\/wp-json\/wp\/v2\/posts\/15781\/revisions"}],"predecessor-version":[{"id":15794,"href":"https:\/\/yourchennai.com\/index.php\/wp-json\/wp\/v2\/posts\/15781\/revisions\/15794"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/yourchennai.com\/index.php\/wp-json\/wp\/v2\/media\/15782"}],"wp:attachment":[{"href":"https:\/\/yourchennai.com\/index.php\/wp-json\/wp\/v2\/media?parent=15781"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/yourchennai.com\/index.php\/wp-json\/wp\/v2\/categories?post=15781"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/yourchennai.com\/index.php\/wp-json\/wp\/v2\/tags?post=15781"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}